David Hogness

Research Hogness was essential to understanding the ontogeny of Drosophila melanogaster (fruit fly). He examined the role of the hormone ecdysone in the development of the fruit fly. In 1978, Hogness and his group identified the TATA box (Goldberg-Hogness box) as the start sequence for the transcription of genes in eukaryotes. Hogness' work contributed to the discovery that the genetic material of eukaryotes consists of non-coding (introns) and coding (exons) sections and that the expression of numerous genes is regulated by so-called cis-elements. Hogness contributed to the fusion of genetics, molecular biology, and developmental biology.

Awards 1965 Newcomb Cleveland Prize 1968 Guggenheim Fellow 1976 Member of the National Academy of Sciences 1976 Member of the American Academy of Arts and Sciences 1977 Howard Taylor Ricketts Award 1979 Harvey Lecturer 1984 Genetics Society of America Medal 1992 Membership of the European Molecular Biology Organization (EMBO) 1995 Humboldt Research Award 1995 Darwin Prize Visiting Professor, University of Edinburgh 1997 March of Dimes Prize in Developmental Biology 2002 Lifetime Achievement Award from the Society for Developmental Biology 2003 Thomas Hunt Morgan Medal 2007 International Prize for Biology