Lizzy Caplan

Elizabeth Anne Caplan (born June 30, 1982) is an American actress. Her performances as Virginia E. Johnson in the Showtime series Masters of Sex (2013–2016) and as Libby Epstein in FX on Hulu's Fleishman Is in Trouble have earned her nominations at the Primetime Emmy Awards.

Her first acting role was on the television series Freaks and Geeks (1999–2000). Since then, she had series-regular roles in several television series including Related (2005–2006), Party Down (2009–2010; 2023), Das Boot (2018), Castle Rock (2019), Truth Be Told (2019), Fatal Attraction (2023), and Zero Day (2025).

Caplan's film breakthrough came with her role as Janis Ian in Mean Girls (2004). Her other film appearances include My Best Friend's Girl (2008) Cloverfield (2008), Hot Tub Time Machine, 127 Hours (both 2010), Save the Date, Bachelorette (both 2012), The Interview (2014), Now You See Me 2, Allied (both 2016), Cobweb (2023) and Now You See Me: Now You Don't (2025).

Early life Elizabeth Anne Caplan was born on June 30, 1982, in Los Angeles, California, and grew up in its Miracle Mile district. Her family are Reform Jews of Ashkenazi Jewish descent. She had a Bat Mitzvah and attended Jewish summer camp. Her father, Richard Caplan, was a lawyer and her mother, Barbara (née Bragman), was a political aide. She is the youngest of three children with a brother, Benjamin, and a sister, Julie. Her mother died of cancer when she was 13 years old. Her uncle was publicist Howard Bragman.

Caplan attended Alexander Hamilton High School in Castle Heights, and attended the school's Academy of Music. She first focused on playing the piano, then later decided to pursue drama. She was also on her school's soccer team. She graduated in 2000, but did not attend college because she wanted to focus on acting. Due to her performance, her character became the girlfriend of Jason Segel's character. She then had a series of guest appearances on numerous shows, and appeared in Jason Mraz's music video "You and I Both". In 2000 she appeared in her first film From Where I Sit which was released straight to television. In 2001, she played Tina Greer in an episode of Smallville, and reprised her role on the show in 2003. She appeared in two episodes of the ABC series Once and Again. In 2003, she starred in the television series The Pitts, playing Faith Pitt. She gained wider notice for playing Janis Ian in the 2004 film Mean Girls. She played Avery Bishop in the second season of Tru Calling.

In 2005, Caplan played troubled sister Marjee Sorelli in Related, a one-hour comedy-drama on The WB that was canceled after one season. In 2006, she starred as Sara Weller in the thriller film Love Is the Drug and was named one of "10 Actors to Watch" by Variety. After Related ended, Caplan was cast in the CBS sitcom The Class, which premiered in September 2006 and lasted for one season. She played Kat Warbler, one of several elementary school friends that reunite after 20 years.

In early 2012, Caplan premiered two films at the Sundance Film Festival: Save the Date and Bachelorette. Also in 2012, she appeared as Julia in several episodes of the Fox sitcom New Girl.

She played Agent Lacey in the 2014 film The Interview.

Masters of Sex (2013–2016)

In 2013, she began playing 1960s human sexuality pioneer Virginia E. Johnson on the Showtime series Masters of Sex. Caplan also provided her own vocals for a cover version of the song "You Don't Know Me" in the Masters of Sex episode "Phallic Victories". Her performance on the show was well-reviewed, and on July 10, 2014, she was nominated for the Primetime Emmy Award for Outstanding Lead Actress in a Drama Series.

Caplan was cast in her role as Johnson before they signed her co-star Michael Sheen as William H. Masters because he was busy working on another production. Producer Sarah Timberman said of Caplan, "The minute we met Lizzie we thought that she just embodied so much of the spirit of Virginia Johnson." Caplan also stated herself that as a single woman pursuing her career above a family, she identified with many of Johnson's characteristics.

Virginia Johnson had worked alongside William Masters as they completed research of human sexual response and sexual dysfunction beginning in the late 1950s. To learn about the characters they were portraying, Caplan along with her other co-stars read Thomas Maier's 2009 biography Masters of Sex. The author also allowed Caplan to listen to some of his interview tapes with Johnson. Caplan also attempted to spend some time with Johnson before she died in 2013, but Johnson was ambivalent about the development of the show. Maier stated that the developers of the show have remained mostly accurate to his book and have included other events that are historically relevant to St. Louis, where the series takes place and where Masters and Johnson lived. Caplan has discussed becoming comfortable with the large number of sex scenes in Masters of Sex.

Her portrayal earned her nominations for the Primetime Emmy Award, Satellite Award and Critics' Choice Television Award, all for Outstanding Lead Actress.

Personal life Caplan dated actor Matthew Perry from 2006 to 2012. She became engaged to British actor Tom Riley in New York in May 2016. They met in January 2015 while Caplan was filming Now You See Me 2 in London and made their red carpet debut as a couple at the Prague Opera Ball in February 2016. They married in September 2017 and had a son born in 2021.

Filmography

Film Year Title RoleNotes 2002 Orange County Party Girl 2004 Mean Girls Janis Ian 2006 Love Is the Drug Sara Weller 2007 Crashing Jacqueline 2008 Cloverfield Marlena Diamond My Best Friend's Girl Ami 2009 Crossing Over Marla2010 Hot Tub Time Machine April Drennan The Last Rites of Ransom Pride Juliette Flowers 127 Hours Sonja Ralston 2011 High Road Sheila 2012 Save the Date Sarah Bachelorette Gena Myers 3, 2, 1... Frankie Go Boom Lassie Queens of Country Jolene Gillis Item 47 Claire Wise Short film 2014 The Interview Agent Lacey 2015 The Night Before Diana 2016 Now You See Me 2 Lula May Allied Bridget Vatan 2017 The Disaster Artist Herself Cameo 2018 Extinction Alice 2022 The People We Hate at the Wedding Marissa 2023 Cobweb Carol 2025 Now You See Me: Now You Don't Lula May 2026 Drag Post-production

Television Year Title Role Notes 1999–2000 Freaks and Geeks Sara 4 episodes 2000 From Where I Sit Lily Television film 2001 Undeclared Beautiful girl Episode: "Prototype" Once and Again Sarah Episode: "Tough Love" 2001–2003 Smallville Tina Greer 2 episodes 2002 Everybody's Doing It Angela Television film 2003 The Pitts Faith Pitt Main role 2005 Tru Calling Avery Bishop 4 episodes 2005–2006 Related Marjee Sorelli Main role 2006 Family Guy Woman arguing with Quagmire (voice) Episode: "Chick Cancer" 2006–2007 The Class Kat Warbler Main role 2006–2009; 2026 American Dad! Debbie (voice) 5 episodes 2008 True Blood Amy Burley Main role (season 1) The Life & Times of Tim (voice) Episode: "Insurmountable High Score/Tim vs. the Baby" 2009–2010; 2023 Party Down Casey Klein Main role (seasons 1–2); guest star (season 3) 2010–2011 Childrens Hospital Harmony / Casey Klein 2 episodes 2011 The Cleveland Show Patty Donner (voice) Episode: "The Essence of Cleveland" Mr. Sunshine Vivian Cornelli Episode: "Ben and Vivian" Wainy Days Arielle Episode: "Kelly and Arielle – Part 2" 2012 New Girl Julia Cleary 4 episodes 2013 Newsreaders Anya Turpo Episode: "Hedge Fun" 2013–2014 The League Rebecca Ruxin 3 episodes 2013–2016 Masters of Sex Virginia E. Johnson Main role; also producer 2014 Kroll Show Signing Bonus contestant #1 Episode: "Krolling Around with Nick Klown" Comedy Bang! Bang! Herself Episode: "Lizzy Caplan Wears All Black & Powder Blue Espadrilles" 2017 The Simpsons Virginia Johnson (voice) Episode: "Kamp Krustier" Angie Tribeca Deirdre Episode: "If You See Something, Solve Something" Ill Behaviour Nadia 3 episodes I'm Sorry Jessica Episode: "Too Slow" 2018 Das Boot Carla Monroe Main role (season 1) 2019 Castle Rock Annie Wilkes Main role (season 2) 2019–2020 Truth Be Told Josie and Lanie Burhman Main role 2021–2022 Inside Job Reagan Ridley (voice) Main role 2022 Fleishman Is In Trouble Libby Miniseries 2023 Fatal Attraction Alex Forrest Main role 2025 Zero Day Alexandra Mullen Main role Far Cry Main role

Audio +YearTitleRoleNotes2025 The CommuterAmy NicholsMain role

Awards and nominations