Jacques Dubochet

Jacques Dubochet (born 8 June 1942) is a retired Swiss biophysicist. He is a former researcher at the European Molecular Biology Laboratory in Heidelberg, Germany, and an honorary professor of biophysics at the University of Lausanne in Switzerland. He received the Royal Photographic Society Progress Medal, alongside his colleagues Professor Joachim Frank and Dr Richard Henderson, in 2018 for 'an important advance in the scientific or technological development of photography or imaging in the widest sense'.

Career Dubochet started to study physics at the École polytechnique de l'Université de Lausanne (now École polytechnique fédérale de Lausanne) in 1962 and obtained his degree in physical engineering in 1967.

From 1978 to 1987, Dubochet was group leader at the European Molecular Biology Laboratory in Heidelberg, then part of West Germany.

During his career, Dubochet developed technologies in cryo-electron microscopy, cryo-electron tomography and cryo-electron microscopy of vitreous sections. These technologies are used to image individual biological structures such as protein complexes or virus particles.

In 2014, Dubochet received EMBL's Lennart Philipson Award. Describing his career in 2015, Professor Gareth Griffiths, his colleague at EMBL explained: "Jacques had a vision. He found a way of freezing thin films of water so fast that crystals had no time to form [that could damage samples] [...] over time the technique has become increasingly important to life science research, and it is clear today it is Nobel Prize-worthy."

At the end of November 2021, the Dubochet Center for Imaging (DCI), which bears his name, was launched by the Swiss Federal Institute of Technology in Lausanne, the University of Lausanne and the University of Geneva. Just a few weeks later, the DCI was able to make a significant contribution to deciphering the Omicron variant of the COVID-19 virus.

Personal life Dubochet is married with two children.

Dubochet is a member of the Social Democratic Party of Switzerland, and a member of the municipal parliament of Morges, where he holds a seat on the supervisory committee. He is also part of the climate movement as a member of the Grandparents for Future and emphasized the urgency of saving our societies.