William Hugh Feldman

William Hugh Feldman (November 30, 1892, in Glasgow, Scotland – January 15, 1974, in Rochester, Minnesota) was a doctor of veterinary medicine known for world-renowned achievement in two distinct fields, veterinary pathology and chemotherapy of experimental tuberculosis. He also made important contributions to the treatment of leprosy.

Biography In 1894 he immigrated with his mother to the United States, where they settled in a small frontier town in western Colorado. There he grew up and graduated from high school. At Colorado Agricultural College (now named Colorado State University), he matriculated in 1913, graduated with a D.V.M. in 1917, joined the faculty in 1917, and received an M.Sc. in 1926. From 1917 to 1927 he taught laboratory classes in pathology and bacteriology and also directed the band at College Agricultural College, with the exception of a leave of absence when in 1920 he studied pathology under Aldred Scott Warthin at the University of Michigan Medical School. which "was the first of its kind published in the English language" and "was acclaimed by reviewers in veterinary and medical journals all over the world." He was the author or co-author of approximately 300 research papers.

Feldman at the Mayo Clinic suggested to Selman Waksman to search for antibiotics that could effectively treat tuberculosis. Waksman was reluctant to do research on a potentially deadly bacterium such as Mycobacterium tuberculosis, the causative pathogen of tuberculosis. When Selman's student Albert Schatz learned about this he insisted that he should be allowed to work on an anti-tuberculosis drug, to which Waksman agreed. Feldman gave Schatz H-37, the most virulent tuberculosis bacterial strain in humans.

Under Waksman's direction, Schatz isolated, from the Rutgers Agriculture School's farm soil, a Streptomyces griseus strain that produced an antibiotic.

For one year from 1941 to 1942 Feldman was the president of the International Association of Medical Museums (renamed in 1955 the International Academy of Pathology). For one year from 1952 to 1953 he was the president of the American Association of Pathologists and Bacteriologists (AAPB). He made photographs of Sir William Osler, as well as Osler's home, laboratory, and instruments. Feldman made photographic portraits of many prominent physicians, especially pathologists, and medical researchers, including 14 Nobel Prize winners. He delivered in 1941 the John W. Bell Memorial Tuberculosis Lecture and in 1946 the Harben Lectures at the Royal Institute of Public Health and Hygiene. Colorado A&M (renamed from Colorado Agricultural College) gave him in 1945 an honorary D.Sc. and in 1950 made him an Honor Alumnus.

In Colorado, Feldman married Esther Marsh Dickinson (1895–1932). Their daughter Esther Isabelle Feldman (1918–1960) married and had two children. William Hugh Feldman's second wife was Ruth Elaine Harrison. They had a son, William Harrison Feldman (born in 1938), who married Diane V. Nemeczek in 1973.

Selected publications Articles

(over 500 citations)

Books