About Isaac Gregory
Lived 1737 – 1800. Isaac Gregory was an American military leader and politician.
Isaac Gregory (c. 1737–1800) was a politician, Senator in the North Carolina General Assembly, and Brigadier General in the North Carolina militia during the American Revolution. He represented his county for ten terms in the senate between 1782 and 1795. He was an active Federalist and delegate to the constitutional conventions of 1788 and 1789.
Gregory's first wife was Elizabeth Whedbee (some sources say she was a daughter of Caleb Sawyer). His second wife was Sarah Lamb. His children were William, Isaac, Mary, Sarah, Penelope, and Harriett. He died in April 1800 and was buried on his plantation, Fairfax (often called Fairfield), in Camden County. The Fairfax plantation dates from the 1740s.
Military service During the Revolutionary War, he held the following positions: Lt. Colonel in the Pasquotank County Regiment of the North Carolina militia (1775) Colonel over the 2nd Pasquotank County Regiment of the North Carolina militia (1775-1777) Colonel over the Camden County Regiment of the North Carolina militia (1777-1779) Brigadier General over the Edenton District Brigade of the North Carolina militia (1779-1783)
He nearly died while leading the Edenton District Brigade at the Battle of Camden in South Carolina when his horse was shot from under him and he was bayonetted. General Charles Cornwallis reported him dead. The British assumed he was going to die but he recovered.
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Important facts
Contemporaries
People whose lives overlapped Isaac Gregory's
Frequently asked questions
Who was Isaac Gregory?
US Colonial Brigadier General
When was Isaac Gregory born?
Isaac Gregory was born in 1737 in Pasquotank County.
When did Isaac Gregory die?
Isaac Gregory died in 1800 in Camden County.
What was Isaac Gregory's occupation?
Isaac Gregory was a military leader and politician.
What nationality was Isaac Gregory?
Isaac Gregory was American.
Sources & further reading
Cite this page
APA: Biography.guide. (2026). Isaac Gregory. https://biography.guide/isaac-gregory/
MLA: "Isaac Gregory." Biography.guide, https://biography.guide/isaac-gregory/.
Chicago: "Isaac Gregory." Biography.guide. https://biography.guide/isaac-gregory/.
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