Ernest Lyman Scott

Education and academic career Scott was born in Kinsman, Ohio. He attended Ohio Wesleyan University as an undergraduate and received his B.S. in 1902. He received his M.S. from the University of Chicago in 1911, working with Anton Carlson, and left Chicago to begin his faculty career with a brief period teaching at the University of Kansas. In 1912 he moved to a teaching position at Columbia University. He received his Ph.D. from Columbia in 1914 and remained on the faculty until his retirement in 1942, briefly interrupted by World War I service with the American Expeditionary Force in France. Among his notable graduate students is physiologist Albert Baird Hastings.

Role in the discovery of insulin Scott's work with Carlson at the University of Chicago subsequently became a subject of controversy over the scientific priority of significant discoveries about insulin and diabetes, which earned Frederick Banting and John Macleod the Nobel Prize in Physiology or Medicine in 1923. Although Scott was only a master's student, he worked relatively independently in the Carlson laboratory, using dogs with surgically disrupted pancreas as animal models to measure his efforts to isolate a hypothesized anti-diabetic "active principle" found in pancreatic secretions. Evidence from his 1911 master's thesis suggests that he did successfully isolate a protein with observable clinical benefits in his experimental diabetic dogs, which by his description must have been insulin. Instead, while departing for his new position in Kansas, Scott left his thesis with Carlson, who published a version in Scott's name in 1912 in the American Journal of Physiology.

In their subsequent work on insulin and diabetes, Frederick Banting and Charles Best expanded upon the themes in Scott's work and cited the 1912 paper. contending that their role in the discovery had been overlooked and earlier work undercited. Scott's wife self-published a book on the subject years later called Great Scott: Ernest Lyman Scott's work with insulin in 1911.

Personal life Scott's wife Aleita Hopping Scott also held a Ph.D. in physiology and shared his interest in plants and gardening. After Ernest Scott's retirement from Columbia, the couple established a reputation as horticulturists, extensively documenting their garden at their home in New Jersey. Ernest Scott served as the founding president of the National Chrysanthemum Society of America and Aleita co-founded the American Primrose Society.

Ernest Scott died in 1966. His papers are held by the National Library of Medicine and the New York Botanical Garden.