About Ephraim of Antioch
Lived 401 – 545. Ephraim of Antioch was a Byzantine presbyter.
Saint Ephraim of Antioch (, born - died 8 June 545 AD), also known as Saint Ephraim of Amida (, Syriac: ܐܦܪܝܡ ܐܡܕܝܐ), was the Patriarch of Antioch, and head of the Greek Orthodox Church of Antioch, from 527 until his death in 545. He is venerated as a saint in the Eastern Orthodox and Catholic Churches. His feast day is 8 June.
Biography Early life Ephraim was the son of a certain Appianus, and was born in the city of Amida in the fifth century, where he became fluent in both Greek and Syriac. Ephraim was later employed in the civil government, and served as a military general during the reigns of Emperor Anastasius and his successor Emperor Justin I. In 522, Ephraim was appointed comes Orientis by Emperor Justin and undertook stern measures against the Blues, a chariot racing faction, who had rioted earlier that year. Rioting within the city ceased as a result of Ephraim's actions, The saint awoke the stone-cutter who revealed he had formerly been a bishop and prophesied that Ephraim would become Patriarch of Antioch. and was consecrated Patriarch of Antioch in April/May 527.
Patriarch of Antioch In 528, Antioch was struck by another earthquake, during which under 5000 people were killed, and the saint helped to rebuild the city once more. Antioch continued to suffer earthquakes and many fled the city, however, Ephraim commanded the people to write "May Christ be with us" over the doors of their houses. Non-Chalcedonians rioted in Antioch in 531 and attacked the patriarchal palace, but were driven off by the comes Orientis. Ephraim wrote to Anthimus, Archbishop of Trebizond, prior to his consecration as patriarch of Constantinople on the natures of Christ and the heresy of Eutychianism, and reminded him of the importance of the Council of Chalcedon. Later, Anthimus became patriarch in 535 and adopted non-Chalcedonianism, which led Ephraim to send Sergius of Reshaina with a letter to Rome to meet with Pope Agapetus I and warn him that non-Chalcedonians had secured control of the Churches of Alexandria and Constantinople. Agapetus consequently intervened and Anthimus was deposed in 536. the saint undertook a tour of Syria and Mesopotamia alongside a contingent of soldiers to enforce the Council of Chalcedon and persecute its opponents, and travelled to Chalcis, Beroea, Hierapolis, Batnae, Edessa, Sura, Callinicum, Theodosioupolis, Constantina, and Amida. Ephraim had non-Chalcedonian monks driven out from their monasteries in the middle of winter, imprisoned those who refused to accept the council, and erected pyres in some cases. The stylite built a bonfire and argued he and the saint should both enter the bonfire to test who was right, to which Ephraim put his omophorion in the fire.
At this time, according to Michael the Syrian, Ephraim was sent as an ambassador to Al-Harith ibn Jabalah, King of the Ghassanids by Emperor Justinian I, and unsuccessfully attempted to persuade the king to accept the Council of Chalcedon. The Sasanian government captured John and transferred him to Ephraim, In 537/538, Ephraim held a synod at Antioch, which was attended by 132 bishops, and declared his approval of the synod held at Constantinople in 536 and condemned Severus of Antioch. Ephraim then attended the Synod of Gaza alongside Hypatius, Archbishop of Ephesus, and Patriarch Peter of Jerusalem and condemned and deposed Patriarch Paul of Alexandria. The saint initially refused to agree to the edict, however, the emperor threatened Ephraim with deposition, after which he agreed to condemn the Three Chapters, and wrote to Pope Vigilius to declare he had only agreed under force. Ephraim died in the following year.
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Important facts
People in Ephraim of Antioch's life
Named in this biography and alive at the same time
Contemporaries
People whose lives overlapped Ephraim of Antioch's
Frequently asked questions
Who was Ephraim of Antioch?
Greek Orthodox Patriarch of Antioch
When was Ephraim of Antioch born?
Ephraim of Antioch was born in 401 in Amida.
When did Ephraim of Antioch die?
Ephraim of Antioch died in 545.
What was Ephraim of Antioch's occupation?
Ephraim of Antioch was a presbyter.
What nationality was Ephraim of Antioch?
Ephraim of Antioch was Byzantine.
Sources & further reading
· Wikipedia: Ephraim of Antioch
Cite this page
APA: Biography.guide. (2026). Ephraim of Antioch. https://biography.guide/ephraim-of-antioch/
MLA: "Ephraim of Antioch." Biography.guide, https://biography.guide/ephraim-of-antioch/.
Chicago: "Ephraim of Antioch." Biography.guide. https://biography.guide/ephraim-of-antioch/.
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