Sophie Postel-Vinay

Sophie Postel-Vinay is a French physician and scientist at the Institut Gustave Roussy where she has led an ATIP-Avenir team since 2018. She works on oncology and the development of new drugs and is an expert in early clinical trials. She was the 2019 winner of the Irène Joliot-Curie Prize in the “young woman scientist” category.

Biography Postel-Vinay earned her medical degree from the University René Descartes Paris V in 2010. As member of Olivier Delattre's team at the Institut Curie, she contributed to important human genetic work on Ewing's sarcoma, which led to the identification of loci associated with the risk of developing this pediatric tumor (published in the journal Nature Genetics in 2012). After her internship, she did a PhD thesis at the Institute of Cancer Research, London, as part of the team of Alan Ashworth, focusing on DNA repair and synthetic lethality. She completed her post-doctoral fellowship in Paris and spent 18 months at the Royal Marsden Hospital in London in Professor Stanley Kaye's drug development unit.

She defended her dissertation, titled Synthetic lethality and functional study of DNA repair defects in ERCC1-deficient non-small-cell lung cancer, in December 2016. Her research was directed by Fabrice André and Postel-Vinay received an ESMO Translational Research Fellowship for her dissertation.

She is an expert on early clinical trials