Sir William Clayton, 1st Baronet

Sir William Clayton, 1st Baronet (died 1744) of Marden Park, Surrey and later Harleyford, was an English politician who sat in the House of Commons from 1715 to 1744.

Clayton was the eldest surviving son of William Clayton of Hambleden, Buckinghamshire. He married Martha Kenrick, the daughter of John Kenrick, a London merchant. He was the nephew and heir of Sir Robert Clayton, a wealthy banker and former Lord Mayor of London who had bought the manor of Bletchingley in 1677, and with it control of both seats in the parliamentary borough of Bletchingley. In 1735 he also bought the manor of Harleyford, near Great Marlow, which gave him control of one of the two parliamentary seats of the borough of Great Marlow.