Peter Howley

Peter Maxwell Howley (born October 9, 1946) is an American pathologist, virologist, and professor at Harvard Medical School. He has been president of the American Society for Virology and the American Society for Investigative Pathology and a co-editor of the Annual Review of Pathology: Mechanisms of Disease.

Biography Howley was born in New Brunswick, New Jersey. He graduated in 1968 from Princeton University with an A.B. in chemistry and in 1970 from Rutgers University with an M.M.S. (Master of Medical Science) degree. In 1972 he graduated with an M.D. from Harvard Medical School. From 1972 to 1973 he worked as an intern in pathology at Massachusetts General Hospital. He was a research associate from 1973 to 1975 at the National Institute of Allergy and Infectious Diseases (NIAID) in Bethesda, Maryland. In 1977 he was granted board certification in anatomic pathology. At the NCI's Laboratory of Pathology, Howley was from 1975 to 1976 a resident, from 1976 to 1977 a junior staff pathologist, from 1977 to 1979 a senior investigator, and from 1979 to 1984 Chief of the Viral Oncology and Molecular Pathology Section. From 1984 to 1993 he was Chief of the NCI's Laboratory of Tumor Virus Biology. In 1991, Howley became the George Fabyan Professor of Comparative Pathology at Harvard Medical School. He was the president of the American Society for Virology from 1998 to 1999 and the president of the American Society for Investigative Pathology in 2006. By 2009 he was the Shattuck Professor of Pathology.

Howley is considered to be a leader in research on papillomaviruses. Howley and his co-workers created gene maps of many species of papillomaviruses and analyzed their transcription patterns and systems of transcription regulation. The research identified papillomavirus oncogenes and the molecular mechanisms of their damaging effects. This work is considered fundamental for the understanding of the pathogenesis of papillomaviruses at the molecular level.

His research also involves assessing the roles of the E6AP/UBE3A ubiquitin ligase in human neurogenetic disorders. He was a co-editor of the Annual Review of Pathology: Mechanisms of Disease from 2007–2015. He is a member of the editorial board of the Proceedings of the National Academy of Sciences.

Awards and honors 1983 — Warner-Lamber/Parke-David Award of the American Society for Experimental Pathology 1986 — Wallace P. Rowe Award of the National Institute of Allergy and Infectious Diseasesfor 1997 — Member, American Society for Clinical Investigation 1993 — Member of the National Academy of Sciences 1994 — Paul Ehrlich and Ludwig Darmstaedter Prize (also awarded to Harald zur Hausen) 1996 — Fellow of the American Academy of Arts & Sciences 2004 — Rous-Whipple Award of the American Society for Investigative Pathology 2011 — Keynote speaker at the Convocation Ceremony of the Robert Wood Johnson Medical School 2015 — NCI Outstanding Investigator Award, National Cancer Institute

Selected publications 1980 1981 1982 1985 1986 1989 1990 1991 1991 1992 1995 1997

1999