Noel Rose

Noel R. Rose (December 3, 1927 – July 30, 2020), was an American immunologist, pathologist, and molecular microbiologist. He is widely known for pioneering autoimmunity during the 1950s and made several contributions to the field of autoimmunity, which brought in the modern era of research into autoimmune disease. He is often referred to as the "Father of Autoimmunity".

Early life Rose was born in Stamford, Connecticut, on December 3, 1927. After graduating from Stamford High School, he attended Yale University and graduated with his Bachelor of Science, and then the University of Pennsylvania, where he achieved his Ph.D. He married soon after. It took him ten years to get his M.D. from the University of Buffalo School of Medicine as he was given research funding for his discovery of autoimmunity.

Career During the 1950s, he experimented with an antigen, called Thyroglobulin, on experimental rabbits and discovered an autoantibody that affected the thyroid gland, this was the first instance of autoimmunity. His research on the genetic basis of autoimmune disease at Wayne State University School of Medicine during the 1970s revealed that the major histocompatibility complex determined the risk of all autoimmune disease. former editor of Clinical Immunology and was editor of The Year in Immunology. He was also a professor in the Department of Pathology and professor in the W. Henry Feinstone Department of Molecular Microbiology and Immunology. At one point, he served as the chairman of the Autoimmune Disease Coordinating Committee of the National Institutes of Health and principal advisor to the former U.S. NIH Director Dr. Elias A. Zerhouni. In 2015, he retired from Johns Hopkins and was working as a member of the Department of Pathology at Brigham and Women's Hospital.