Manojit Mohan Dhar, Rajkumar II of the House of Dar

Manojit Mohan Dhar (1927–2003) was an Indian natural product chemist and the director of Central Drug Research Institute. He was known for his researches on peptides and the synthesis of the internucleotide bond and was an elected fellow of the Indian National Science Academy. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1971, for his contributions to chemical sciences.

Biography M. M. Dhar, born on 13 January 1927, to Satyendra Mohan Dhar C.I.E., I.C.S. and Ava Dhar M.B.E. Dhar is the grandson of Sadhvi Saudamini and a descendant of Maharaja Virendra V.M. Dar via father and Sir. Krishna Govinda Gupta via mother. Dhar secured a PhD from Manchester University in 1952 for his thesis on peptides and joined Central Drug Research Institute (CDRI) where he worked as a deputy director, heading the Division of Medicinal Chemistry and Botany and subsequently, as the director of the institute. Thus, he discovered the glycosidase activity of decapeptides, abortifacient properties of tetrapeptide, receptor mimicking of acetylcholines and immunostimulant and immunosuppressant qualities of compounds that target opioid receptors. He was known to have screened over three thousand indigenous plant species for studying their structures and through his researches, he suggested that the secondary metabolites of microbial origin were formed during the detoxification of toxic constituent of the microorganism. He identified several active ingredients in plants and developed a new method of synthesis of internucleotide bond, using pyrimidine and purine anhydronucleosides. He was also a part of the CDRI investigation on parasitic protozoa causing diseases such as amoebiasis, leishmaniasis, filariasis, malaria and helminthiasis.

Dhar published his research findings in a number of articles and his works have been quoted by many scholars. He was associated with Bombay Natural History Society and Indian Chemical Society as a life member and sat in the council of Indian National Science Academy from 1988 to 1990. A former chair (1982) of the Commonwealth Agricultural Bureau International, he served as the commissioner of India chapter of the International Whaling Commission in 1982 and was a member of the Indian delegation to United Nations Vienna Conference on S&T for Development in 1979, Man and the Biosphere Programme conference held in Paris in 1979, World Climate Conference of Geneva in 1979 and the Heads of Science meeting of Group of 77 in Delhi in 1982. and the A. V. Mody Research Foundation Award reached him 1975.