Leonard Lerman

Life and career Lerman was born and raised in Pittsburgh, the son of Freamah and Meyer Lerman, Jewish immigrants from Ukraine. This discovery has shaped much of science's understanding about how drugs and mutagens interact with DNA.

Later, during a sabbatical at the University of Cambridge, Lerman had a chance to work with later Nobel prize winners Sydney Brenner and Francis Crick.

Lerman led a productive research program at Vanderbilt University in Nashville, the University of Colorado Health Sciences Center in Denver and SUNY Albany, the State University of New York at Albany. Lerman's lab crew included at least one Nobel prize winner, Sidney Altman, and another, Tom Maniatis, who also became one of the leading molecular biologists of his time.

Lerman's last major effort, begun with Stuart Fischer at SUNY, was the invention of denaturing gradient gel electrophoresis (DGGE), a technique used to separate DNA molecules. DGGE is widely used by scientists who wish to ascertain biodiversity in microbial communities.

Dr. Lerman was also a senior member of one of the first biotechnology companies, the Genetics Institute, co-founded by one of his students, Tom Maniatis. Dr. Lerman was a member of the National Academy of Sciences, USA.