Jovan Santos-Knox

Professional career

Winnipeg Blue Bombers (first stint) Santos-Knox was signed by the Winnipeg Blue Bombers after driving nine hours with his father to a tryout camp which his father had found in Charlotte, North Carolina. He started his rookie season on special teams but by the end of the regular season was a starting linebacker and was being praised by coach Mike O'Shea and media for big plays at big moments of games. After recording 10 tackles and 3 sacks against Toronto on July 27, 2018, Santos-Knox was named the CFL's third star of the week.

Edmonton Eskimos Santos-Knox spent the 2019 season with the Edmonton Eskimos where he played in three regular season games. After the CFL canceled the 2020 season due to the COVID-19 pandemic, he chose to opt-out of his contract with the Edmonton Eskimos on August 27, 2020.

Hamilton Tiger-Cats On February 6, 2021, it was announced that Santos-Knox had signed with the Hamilton Tiger-Cats.

Ottawa Redblacks On February 7, 2023, it was announced that Santos-Knox had signed with the Ottawa Redblacks. He played in three seasons where he recorded 209 total tackles, five sacks, and two interceptions. He was released on January 30, 2026.