Jacqueline M. Cole

Jacqueline Manina Cole is the Head of the Molecular Engineering group in the Cavendish Laboratory at the University of Cambridge. Her research considers the design of functional materials for optoelectronic applications.

Early life and education Cole earned her first degree in chemistry at Durham University in 1994. She remained there for her graduate studies, completing a PhD in 1997 (Grey College). Her thesis, Structural studies of organic and organometallic compounds using x-ray and neutron techniques, described the structure-property relationships of non-linear optical materials, including studies of transition metal complexes. She was supervised by Judith Howard. Cole moved to the University of Cambridge as a Junior Research Fellow in St Catharine's College, Cambridge in 2001. Here she began to investigate photo-crystallography. In her spare time, Cole completed a bachelor's degree in mathematics at the Open University. After the bachelor's degree in mathematics, Cole earned diplomas in statistics (2004), physics (2008) and astronomy (2006) as well as a second bachelor's degree in engineering (2014) from the Open University. Cole earned a second doctorate in physics at the University of Cambridge in 2010.

Career and research As a Royal Society University Research Fellow, Photo-activation can result in structural changes that are irreversible, reversible, long-lived (microsecond lifetimes) and very short-lived (nanosecond lifetimes). In 2008 she was appointed Vice-Chancellor's Research Chair at the University of New Brunswick.

Cole is interested in dye-sensitized solar cells, nonlinear optics and optical data storage. She investigated how data mining and Quantum chemical calculations could be used to predict which dyes might perform best. She uses the EPSRC National Service for Computational Chemistry Software. She has looked to use some of the dyes, in particular p-phenylene, as a laser.

Whilst inorganic materials dominate the photonic device industry, the need for high-speed telecommunications has exceed their limitations. Organic electronic materials have a significantly faster response time. She designed cells that used metal-free organic dyes and achieve a 14.3% efficiency. The cells incorporated an organic sensitiser, MK-44, and an organic dye, MK-2, based on thiophenylcyanoacrylate. Cole optimised the anchoring characteristics of the dye on titanium dioxide nanoparticles to improve charge-transfer pathways.

Her early work considered how molecular structure impacted second-harmonic generation. Cole studied the origins of the nonlinear optics observed in N-methylurea, where solid-state intermolecular interactions and electron-donation from the methyl group separate it from the reference material urea. She has investigated the molecular design rules of organometallic second-harmonic generation active materials.

In 2018 Cole was appointed a Royal Academy of Engineering Senior Research Fellow. The fellowship is a collaboration between the Science and Technology Facilities Council (STFC), BASF and ISIS neutron source to discover functional materials systematically. As of 2019, Cole leads the Molecular Engineering group in the Cavendish Laboratory.

In 2025, Cole was appointed as the lead for AI in Materials Discovery, Characterisation and Application by the Henry Royce Institute. Awards and honours 2000 British Crystallographic Association Chemical Crystallography Prize 2001 Royal Society University Research Fellowship 2020 Royal Society Clifford Paterson Medal and Lecture