Biography.guide
Home › People › Astrologer › Gironima Spana
Portrait of Gironima Spana

Gironima Spana

1615 – 1659

17th century Italian poisoner

Don't just read it — keep itBiographies to ownE-book · Audio · Video From $7 →

About Gironima Spana

Lived 1615 – 1659 (aged 43–44). Gironima Spana was an astrologer.

Gironima Spana (1615 – 5 July 1659) was a Sicilian poisoner and astrologer. She was the central figure in the infamous Spana Prosecution against a poisoning network of merchant women in Rome who distributed the poison Aqua Tofana to clients who wished to commit murder, in particular women who wished to become widows. After her death 17 January 1651, Spana took over her business. She developed it into a considerable enterprise, with several poison saleswomen active in the business in the 1650s.

Spana was an astrologer of note in Rome, where she was engaged to predict the future and find missing objects by clients in the Roman aristocracy. It is noted that she behaved and dressed in a manner which made her acceptable in the salons of the aristocracy, and it is mentioned how her rich client sent for her in their carriages and that she often travelled around Rome in carriages borrowed from her aristocratic friends.

Prosecution

The poison business was exposed to the Papal authorities with the arrest of one of Spana's poison sellers, Giovanna De Grandis, who was arrested in flagrante 31 January 1659 and imprisoned at the Tor di Nona, where she named Spana during the interrogations.

On 2 February, Spana was arrested and taken to the Papal prison of Tor di Nona, where she was interrogated by the lieuntenant governor Stefano Bracchi. Spana was described as intelligent, self assured and confident. She denied all accusations and stood by her denial for months, despite repeated interrogations and confrontations with her former associates and clients. She was willing to answer questions and talked a lot, but only provided harmless information, such as long, detailed answers of acquaintances, their family history and residence, but never anything which could be seen as incriminating. She was described as much more resilient than her fellow prisoners; in contrast to them, she did not even talk about her guilt in her confession to a priest. Her lack of confession was a problem since law did not permit execution without it. She did not confess until 20 June. She finally signed a long statement of guilt. In regard to the poison, she stated: "I've given this liquid to more people than I’ve got hairs on my head".

The investigation, the Spana Prosecution, continued for several months until March 1660, involving about forty people accused of having sold or used the poison, with Spana and four of her female business associates, Giovanna De Grandis, Maria Spinola, Graziosa Farina, and Laura Crispoldi, executed at the Campo de' Fiori in Rome on 5 July 1659.

Legacy

Gironima Spana and the Spana Prosecution became the subject of sensationalist myths, and she has been confused with her stepmother Giulia Tofana.

In popular culture Gironima Spana and the Spana Prosecution are the fictionalized focus of The Book of Secrets, a historical fiction novel by British author Anna Mazzola, published by Orion Fiction in March 2024.

Biography shop

Don’t just read it —
keep it.

Full-length biographies made to live with: read them, listen on the way to work, watch them tonight.

  • E-book
  • Audio
  • Video
Browse the shop — from $7

Instant download · yours to keep · every purchase keeps this site free

Important facts

Born
1615
Birth century
Died
1659
Occupation

Contemporaries

People whose lives overlapped Gironima Spana's

Frequently asked questions

Who was Gironima Spana?

17th century Italian poisoner

When was Gironima Spana born?

Gironima Spana was born in 1615.

When did Gironima Spana die?

Gironima Spana died in 1659.

What was Gironima Spana's occupation?

Gironima Spana was an astrologer.

Sources & further reading

· Wikipedia: Gironima Spana

· Wikidata: Q110851988

· DBpedia: Gironima Spana

Cite this page

APA: Biography.guide. (2026). Gironima Spana. https://biography.guide/gironima-spana/

MLA: "Gironima Spana." Biography.guide, https://biography.guide/gironima-spana/.

Chicago: "Gironima Spana." Biography.guide. https://biography.guide/gironima-spana/.

Data last updated: 2026-09-20 · Spot an error? Report a correction.

Page generated 2026-09-27 05:27 UTC