Ghanshyam Swarup

Ghanshyam Swarup (born 1953) is an Indian molecular biologist, a J. C. Bose National Fellow and the head of the Ghanshyam Swarup Research Group of the Centre for Cellular and Molecular Biology. He is known for his studies on glaucoma and the discovery of protein tyrosine phosphatase, a new protein influencing the regulation of cell proliferation. Swarup is an elected fellow of the Indian Academy of Sciences, the Indian National Science Academy and the National Academy of Sciences, India. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1996, for his contributions to biological sciences.

Biography

Ghanshyam Swarup, born on 23 November 1953 in the Indian state of Uttar Pradesh, graduated in science from Chhatrapati Shahu Ji Maharaj University and continued his studies there to secure a master's degree before moving to Mumbai to complete his PhD at Tata Institute of Fundamental Research (TIFR). and is the head of Ghanshyam Swarup Group which carries out researches on optineurin and the functional defects caused in humans by its mutations.

Legacy Swarup, while working with Stanley Cohen in the US on cellular signaling mechanisms, is reported to have discovered a new nuclear protein tyrosine phosphatase (PTPase) and his subsequent work demonstrated that the protein plays a part in the regulation of cell proliferation. Later, during his early days at CCMB, he elucidated the molecular cloning of a protein tyrosine phosphatase and its bind with DNA and established the methodology for alternative splicing of a gene to form four different variations of PTPase. and has elaborated on the pathogenesis in the disease from a molecular perspective.

Swarup has published several articles detailing his research findings; ResearchGate, an online repository of scientific articles has listed 81 of them. He is a member of the editorial board of the Journal of Molecular Signaling and is known to be active in the researches done by others. Swarup has mentored several scholars in their doctoral and post-doctoral researches at his research group in CCMB

Awards and honors Swarup, who was elected as a fellow by the National Academy of Sciences, India in 1988, on which he pursues his current researches at CCMB.

Selected bibliography