Edith E. Sproul

Edith E. Sproul, M.D. (October 17, 1907 – January 19, 1999) was an American pathologist whose work with Georgios Papanikolaou of the Cornell University Medical School in New York led to the development of the pap smear.

Life and career Edith E. Sproul was born in 1907 in Passaic, New Jersey. She graduated from Barnard College of Columbia University in 1927, followed by Columbia's College of Physicians and Surgeons in 1931. After a two-year internship at Strong Memorial Hospital in Rochester, New York and a residency in pathology at Presbyterian Hospital, Sproul returned to Columbia as instructor in pathology at the College of Physicians and Surgeons. She remained at Columbia for twelve years and was promoted to the position of associate professor before her departure in 1946. She then moved to the American University of Beirut in Lebanon, where she was appointed full professor and served as acting chair of the department of pathology.

Publications The following is a partial list of publications by Sproul:

Sproul, E.E. (1980) Acid phosphatase and prostate cancer: historical overview. The Prostate, 1(4), 411–413. Sproul, E.E. (1973) Projected multidisciplinary lymphoma study group. Journal of Surgical Oncology, 5(6), 581–582. Sproul, E.E. (1963) Wegener's and Lethal Midline Granulomatosis. JAMA: The Journal of the American Medical Association, 177(13), 921–922. Hudson, P.B., Sanger, G., Sproul E.E. (1959) Effective system of bactericidal conditioning for hospitals. Journal of the American Medical Association, 169(14), 1549–1556. Bickerman, H.A., Sproul, E.E., Barach, A.L. (1959) Effective system of bactericidal conditioning for hospitals. Diseases of the Chest, 33(4), 347. Fiala, A., Fiala, S., Sproul, E.E. (1956) The Action of Corticotropin (ACTH) on Nucleic Acids and Subcellular Elements of the Adrenal Cortex. The Journal of Biophysical and Biochemical Cytology, 2(2), 115–126. Fiala, S., Sproul, E.E., Blutinger, M.E., Fiala, A.E. (1955) Basophilic chromidia and mitochondria in normal and in tumor tissue. The Journal of Histochemistry and Cytochemistry, 3(3), 212–226. Hudson, P.B., Finkle, A.L., Hopkins, J.A., Sproul, E.E., Stout, A.P. (1954) Prostatic cancer. XI. Early prostatic cancer diagnosed by arbitrary open perineal biopsy among 300 unselected patients. Cancer, 7(4), 690–703. Hudson, P.B., Finkle, A.L., Trifilio, A., Jost, H.M., Sproul E.E., Stout, A.P., (1954) Prostatic Cancer: VII. Detection of unsuspected adeno carcinoma in the aging male population. The Journal of the American Medical Association, 155(5), 426–429. Lattes, R., McDonald, J.J., Sproul, E.E. (1954) Non-chromaffin paraganglioma, of carotid body and orbit; report of a case. Annals of surgery, 139(3), 382–384. Lenz, M., Sproul, E.E. (1934) Carcinoma of the tongue with generalized metastases. The American Journal of Surgery, 25(1), 102–106.