Clodoveo Ferri

Clodoveo Ferri (born 22 March 1947)

For an in-depth overview of studies on “HCV, cryoglobulinemia, and lymphoma” go to Overview of the Research Line: from Mixed Cryoglobulinemia (Cryoglobulinemic Vasculitis) to HCV infection, Autoimmunity, and Oncogenesis.

Ferri is a member of the SIR (Italian Society of Rheumatology) and GISC (Italian Group for the Study of Cryoglobulinemias), ALCRI (Italian Association for the Fight against Cryoglobulinemias) and an international fellow of the American College of Rheumatology.

Scientific activity Ferri's work includes clinical and laboratory investigations of different autoimmune and neoplastic diseases; in particular, he investigated the pathogenetic role of some viruses in mixed cryoglobulinemia (cryoglobulinemic vasculitis) and systemic sclerosis (scleroderma). This finding suggested a causative role of HCV in other virus-related extrahepatic manifestations, including autoimmune and lymphoproliferative disorders. The association of HCV with B-cell non-Hodgkin's lymphoma was first demonstrated in 1994. On the basis of these studies, confirmed and expanded by other authors worldwide, Clodoveo Ferri suggested the term "HCV syndrome", which refers to particular autoimmune-neoplastic disease complex triggered by HCV infections in predisposed individuals.

The association of HCV with different diseases represents a good model of study of other virus-driven autoimmune, lymphoproliferative, and neoplastic disorders.

Ferri has published over 450 scientific papers in international journals, see PubMed 1994: identification of HCV as a triggering factor in a significant percentage of patients with B-cell non-Hodgkin’s lymphoma. 1993: possible role of HCV in patients with porphyria cutanea tarda, autoimmune hepatitis, autoimmune thyroiditis, and type 2 diabetes. 1999: possible role of parvovirus B19 and CMV in systemic sclerosis (scleroderma). In this respect, significantly higher prevalence of parvovirus B19 infection was originally demonstrated in both bone marrow and skin of scleroderma patients compared to controls.

3. Etiopathogenesis, clinical features, survival, and treatment of mixed cryoglobulinemia syndrome (cryoglobulinemic vasculitis).

5. Role of plasmapheresis and dietetic treatments in some rheumatic disorders (cryoglobulinemic vasculitis, SLE, scleroderma, IgA nephropathy).

6. Impact of COVID19 on autoimmune systemic diseases. Since 2020 Ferri is the coordinator of the COVID-19 & ASD Italian Study Group.

Ferri's scientific production and related Hirsch index (H-index) can be found on Google Scholar Scopus and ScholarGPS.

Personal life Son of Paolo and Marianna (née Paoletti), Ferri is married to Daniela Onofrio and the couple have two children, Paolo and Marianna.