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Clarice Orsini

1453 – 1488

Wife of Lorenzo de' Medici

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About Clarice Orsini

Lived 1453 – 1488 (aged 34–35). Clarice Orsini was an aristocrat.

Clarice Orsini (1453 – 30 July 1488) was the daughter of Jacopo Orsini, and Maddalena Orsini; both from the Orsini family, a great Roman noble house, and was the wife of Lorenzo de' Medici.

Life Clarice and Lorenzo married 4 June 1469, with a four-day celebration. The marriage was arranged by Lorenzo's mother Lucrezia Tornabuoni, who wanted her eldest son to marry a woman from a noble family to enhance the social status of the Medicis. Their marriage was unusual for aristocrats in Florence at the time in that they were nearly the same age. Clarice's dowry was 6,000 florins.

The political nature of her marriage meant that she was often called upon by each side of her family to influence the other. This included Lorenzo helping her brother Rinaldo get selected as Archbishop of Florence. She was also called on by others throughout the area to support their requests to her husband. People sought her support in easing taxes and releasing family members from exile or prison. She would also use her network to gather information about political and military events away from where she was, including troop movements and battles.

Clarice's religious upbringing was a bit in contrast with the humanist ideals of the age popular in Florence. Nevertheless, sources and letters suggest that there was a great deal of affection and respect between her and Lorenzo. Of the ten children born to them, four died in infancy.

During the Pazzi conspiracy, which was aimed at murdering Lorenzo and his younger brother Giuliano, Clarice and her children were sent to Pistoia. (The Pazzis succeeded in murdering Giuliano, but Lorenzo survived the attack, thus the conspirators' plan to replace the Medicis as de facto rulers of Florence failed).

Clarice returned to Rome several times to visit her relatives; she also visited Volterra, Colle Val d'Elsa, Passignano sul Trasimeno, and other places in the 1480s. During these visits, she was treated as a representative of her husband, an unusual role for a woman in that time and place.

On 30 July 1488 she died of tuberculosis in Florence, and was buried two days later. Her husband was not with her when she died, nor did he attend the funeral, because he himself was very ill and was in Bad Filetta near Siena to get cured.

The fact that Lorenzo was away from home when she died, affected even more his mood. Piero da Bibbiena, private chancellor of the Magnificent, wrote the following letter to the Florentine Ambassador in Rome :

In a letter to Pope Innocent VIII he wrote that he dearly missed his late wife. The content of Lorenzo's letter to the Pope is the following:

Issue Clarice and Lorenzo had ten children: Lucrezia de' Medici (Florence, 4 August 1470 – 15 November 1553); married Jacopo Salviati on 10 September 1486 and had 10 children, including Cardinal Giovanni Salviati, Cardinal Bernardo Salviati, Maria Salviati (mother of Cosimo I de' Medici, Grand Duke of Tuscany), and Francesca Salviati (mother of Pope Leo XI). Male twins (March 1471). Their name are unknown, but they lived enough to be baptised. Piero de' Medici (Florence, 15 February 1472 – Garigliano River, 28 December 1503), ruler of Florence after his father's death, called "the Unfortunate" Maddalena de' Medici (Florence, 25 July 1473 – Rome, 2 December 1528), married 25 February 1487 Franceschetto Cybo (illegitimate son of Pope Innocent VIII) and had eight children Contessina Beatrice de' Medici (23 September 1474 - September 1474), died young Giovanni de' Medici (Florence, 11 December 1475 – Rome, 1 December 1521), ascended to the Papacy as Pope Leo X on 9 March 1513. Luisa de' Medici (Florence, 1477 – May 1488), also called Luigia, was betrothed to Giovanni de' Medici il Popolano but died young. Contessina de' Medici (Pistoia, 16 January 1478 – Rome, 29 June 1515); married 1494 Piero Ridolfi (1467 - 1525) and had five children, including Cardinal Niccolò Ridolfi. Giuliano de' Medici, Duke of Nemours (Florence, 12 March 1479 – Florence, 17 March 1516), created Duke of Nemours in 1515 by King Francis I of France.

Their children were taught by Angelo Poliziano for a time. In 1478, he wanted to teach the children humanism, Latin, and Greek, but Clarice insisted on their lessons being more religious, and being delivered in Italian. She had also removed the family and their teacher from Florence after the scare of the Pazzi conspiracy, and he chafed under the exile. In May 1479, she tried to dismiss the tutor over another change in the curriculum, though Lorenzo continued to pay him.

Ancestry

In popular culture She appears in the second season of Medici, played by Synnøve Karlsen. She also appears in the Starz series Da Vinci's Demons played by Lara Pulver.

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Important facts

Born
1453, Monterotondo
Birth century
Occupation

Family & relationships

Spouse
Lorenzo de' Medici

People in Clarice Orsini's life

Named in this biography and alive at the same time

Contemporaries

People whose lives overlapped Clarice Orsini's

Frequently asked questions

Who was Clarice Orsini?

wife of Lorenzo de' Medici

When was Clarice Orsini born?

Clarice Orsini was born in 1453 in Monterotondo.

When did Clarice Orsini die?

Clarice Orsini died on 30 July 1488 in Florence.

What was Clarice Orsini's occupation?

Clarice Orsini was an aristocrat.

Sources & further reading

· Wikipedia: Clarice Orsini

· Wikidata: Q261871

· DBpedia: Clarice Orsini

Cite this page

APA: Biography.guide. (2026). Clarice Orsini. https://biography.guide/clarice-orsini/

MLA: "Clarice Orsini." Biography.guide, https://biography.guide/clarice-orsini/.

Chicago: "Clarice Orsini." Biography.guide. https://biography.guide/clarice-orsini/.

Data last updated: 2026-09-22 · Spot an error? Report a correction.

Portrait: Wikimedia Commons · author & licence

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