Anne Brunet

Anne Brunet (born on November 8)

Personal life Brunet is from Bellegarde sur Valserine, France, uses red wine as an anti-aging strategy, and plays piano and violin. She is a member of the editorial board for Genes & Development.

Research Brunet's lab works on discovering lifespan-regulating genes and their interactions with the environment. Next, she studies how conserved 'pro-longevity genes' (e.g. FOXO transcription factors) regulate longevity in mammals, the regenerative potential of stem cells, and the nervous system. She uses mammalian tissue culture and C. elegans as model systems to study longevity pathways, dietary restriction, and epigenetic (chromatin-state) regulation of longevity by the environment. In addition, she is developing the extremely short-lived African killifish N. furzeri as a new vertebrate model for aging.

The Chan Zuckerberg Initiative awarded a $525,000 research grant to Brunet, along with colleagues Ami Bhatt and K. Christopher Garcia, for their project "Analyzing how inflammation affects the aging brain."

Brunet received the 2022 Lurie Prize in Biomedical Sciences in recognition of work showing "how specific biochemical modifications of the protein structures around which an organism’s DNA is organized can extend its life and that of its descendants".