Sejal Saglani

Sejal Saglani is a British medical researcher who is Professor and Head of the Inflammation, Repair and Development Section at the National Heart and Lung Institute. Her research considers wheeze and severe childhood asthma. She serves as an Honorary Consultant in Paediatric Respiratory Medicine at the Royal Brompton Hospital.

Early life and education Saglani earned her undergraduate degree in medicine at the University of Leicester. She completed her specialist training in the Thames Valley in respiratory medicine, with a focus on paediatrics. She moved to the National Heart and Lung Institute (NHLI) for her graduate studies, where she investigated severe infant and pre-school wheeze. She was awarded the NHLI thesis prize for her doctorate.

Research and career Saglani was awarded a British Lung Foundation Fellowship to develop a model of allergic asthma. which impacts 1 in 10 children in the United Kingdom.

In 2018, Saglani became Head of the Inflammation, Repair and Development (IRD) section at the NHLI. At the NHLI, she continued to study pre-school wheeze and childhood severe asthma. To better understand respiratory disease, she makes use of airway samples from children, as well as neonatal mouse models. By treating newborn mice with farmyard microbes (Acinetobacter lwoffii), Saglani demonstrated that early interventions in children with asthma could reduce their respiratory conditions and prevent them from developing abnormal lung function later in life.

Awards and honours European Respiratory Society Young Investigator Award for Paediatric Research European Respiratory Society Romain Pauwels Award for Translational Asthma Research

Selected publications