Rafael Lorente de No

Rafael Lorente de Nó (April 8, 1902 – April 2, 1990) was a Spanish neuroscientist who advanced the scientific understanding of the nervous system with his seminal research. He was a member of the National Academy of Sciences. Lorente de Nó was an active member of several academic societies, among them the American Physiological Society and the American Association of Anatomists. In 1986, he received the Award of Merit for his life's work.

Notable research and discoveries Seminal research of the structure and function of the cerebral cortex, including the first description of the columnar organization of cortex. He introduced the current terminology of the subfields of the cornu Ammonis of the hippocampus (CA1-4). Studies of the relationship between the nervous system the electrical and chemical basis of nerve functions The first part of the scientific career of Rafael Lorente de Nó was focused on the histological study of the audio-vestibular nuclei and system. He was invited by Róbert Bárány to work with him at Uppsala and was the founder of clinical otorhinolaringlogy in Spain. Indeed, his first stage in the US was to work in the Central Institute for the Deaf at Washington University in St. Louis. Discovery of "recurrent, reciprocal connections" by Golgi's method, and proposed that excitatory loops explain certain aspects of the vestibulo-ocular reflex. Synthesis of tetraethylammonium (TEA) to block potassium channels.