Melissa A. Wilson Sayres

Melissa A. Wilson is an evolutionary and computational biologist and assistant professor at Arizona State University who studies the evolution of sex chromosomes.

Personal life and education Wilson was born in Stillwater, Oklahoma, and lived there until she was five, then moving to Garland, Texas, then Tempe, Arizona, then to Syracuse, Nebraska. and received her B.S. in Medical Mathematics with Honors in May 2005 from Creighton University under Lance Nielsen.

She received her Ph.D. in integrative biology at Pennsylvania State University under her thesis advisor Kateryna Makova in 2011. in 2019. Together they have one daughter. Another discovery is that the Y chromosome is not decreasing in size, which contradicts previously publicised claims that the Y chromosome might disappear.

She also discovered evidence of a Y chromosome population bottleneck in human history. Wilson hypothesised that a possible explanation for this was partially cultural, saying ""Instead of 'survival of the fittest' in a biological sense, the accumulation of wealth and power may have increased the reproductive success of a limited number of 'socially fit' males and their sons."

The lab uses the Gila monster as a model organism to understand the evolution of sex chromosomes. As part of her research, she started a crowdfunding campaign which successfully raised over $10,000 to sequence the Gila monster's DNA. and is the developer of several software packages, including XYalign, for accurately aligning sex chromosomes, and TumorSim, for simulating tumor heterogeneity.

Science communication Wilson is active in public outreach. She is a regular on the ASU "Ask a Scientist" podcast and has been interviewed by the New York Times, The Atlantic, and the Pacific Standard, and transphobia, and against the maltreatment of victims of sexual assault.

Publications and awards

Selected publications

Selected awards Source: 2019 Awardee, Mary Lyon Award, International Mammalian Genome Society 2018 Awardee, SMBE Allan Wilson Junior Award for Independent Research 2018 Awardee Zebulon Pearce Distinguished Teaching Award, Arizona State University 2010 First Place Award, Genome Research poster competition at CSH: The Biology of Genomes 2008 Women In Science and Engineering Outstanding Service Award 2006 The Pennsylvania State University NSF GRFP Incentive Award 2005 Creighton University Outstanding Mathematician Award