Masanobu Yamamoto

is a Japanese optical engineer, inventor, business executive, and rower who competed in the Olympics.

After graduating with a Bachelor of Science in physics from the University of Tokyo in 1973, Yamamoto began his career as an optical engineer for Sony Corp, where he spent nearly 35 years developing optical storage and display systems. From 1973 to 2010, he was a General Manager at Sony. where he was responsible for developing the first commercial spectral flow cytometry system utilizing Purdue's spectral technology. Since 2012 Yamamoto has served as the business development manager for microfluidics Phototek Laboratory Inc. in Kanagawa, Japan.

After retirement from Sony DADC, Yamamoto relocated to West Lafayette, IN, where, in a partnership with J. Paul Robinson, he co-founded Miftek Corporation and continues his work on the expansion of the Blu-ray-related technologies, and the new photon-detection systems for biological applications. He is also an adjunct professor at Purdue University, West Lafayette, Indiana.

In 2012 Yamamoto was admitted to the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows for "outstanding contributions to advanced detection technologies and for his seminal contribution to the design, advancement and manufacture of microfluidic devices."

On Dec 12, 2023 Yamamoto was have been named a fellow of the National Academy of Inventors (NAI).

Yamamoto is a rower. He competed in the men's eight event at the 1976 Summer Olympics.