Linda D. Sharples

Linda Sharples is a British statistician who is Professor of Medical Statistics at the London School of Hygiene & Tropical Medicine. Her research considers statistical analysis of medical interventions. She has provided expert advice to clinical trials on cardiovascular disease, diabetes and cancer.

Early life and education Sharples was trained at the University of Nottingham, where she focussed on mathematics and statistics. Her doctoral research considered robustness and approximation in hierarchical models. She joined Newcastle University as a postdoctoral fellow in 1986.

Research and career In 1989, Sharples joined the Medical Research Council Biostatistics Unit in Cambridge. She was made a programme leader in 2000. In this capacity, she developed statistical methods for assessing health technologies. The outcomes of her research were used to update experimental studies and decision models in the Royal Papworth Hospital NHS Foundation Trust. She applied clinical epidemiology to cardiothoracic transplants. She evaluated surgical procedure and developed multi-state models to describe the history of chronic disease.

In 2013, Sharples left the MRC to join the University of Leeds Clinical Trials Unit as a professor of statistics, where she oversaw the Comprehensive Health Research Division, which focussed on trials in musculoskeletal and cardiovascular medicine. She moved to the London School of Hygiene & Tropical Medicine as a professor of Medical Statistics in 2017. She studies how medical statistics can be used to evaluate different interventions.

Selected publications