About Lefty Guise
Lived 1908 – 1968 (aged 59). Lefty Guise was an American baseball player.
Witt Orison Guise (September 18, 1908 – August 13, 1968), nicknamed "Lefty Guise", was an American professional baseball player. He was a left-handed pitcher for one season with the Cincinnati Reds. He appeared in two major league games. In a twist of irony, he faced 20 different batters in 34 plate appearances, but he faced four future Hall of Famers, including the first two batters. The first batter to face Guise was Enos "Country" Slaughter and he struck him out which is the only strikeout that he had in his career. The next batter he faced was future Hall of Famer Johnny "The Big Cat" Mize. Later in the same game he faced future MVP Marty Marion. In his last game, he faced Mel Ott as well as Carl Hubbell. Guise got his only major league hit off Hubbell, so he accomplished a lot in very few opportunities. He did not record a decision, with a 1.17 earned run average, and one strikeout in innings pitched.
An alumnus of the University of Florida, he was born in Driggs, Arkansas, and died in Little Rock, Arkansas, at the age of 59.
Don’t just read it —
keep it.
Full-length biographies made to live with: read them, listen on the way to work, watch them tonight.
- E-book
- Audio
- Video
Instant download · yours to keep · every purchase keeps this site free
Important facts
People in Lefty Guise's life
Named in this biography and alive at the same time
Contemporaries
People whose lives overlapped Lefty Guise's
Frequently asked questions
Who was Lefty Guise?
American Major League Baseball player
When was Lefty Guise born?
Lefty Guise was born on 18 September 1908 in Driggs, Arkansas.
When did Lefty Guise die?
Lefty Guise died on 13 August 1968 in Little Rock.
What was Lefty Guise's occupation?
Lefty Guise was a baseball player.
What nationality was Lefty Guise?
Lefty Guise was American.
Sources & further reading
Cite this page
APA: Biography.guide. (2026). Lefty Guise. https://biography.guide/lefty-guise/
MLA: "Lefty Guise." Biography.guide, https://biography.guide/lefty-guise/.
Chicago: "Lefty Guise." Biography.guide. https://biography.guide/lefty-guise/.
Data last updated: 2026-09-21 · Spot an error? Report a correction.
Portrait: Wikimedia Commons · author & licence
Page generated 2026-09-27 04:59 UTC