John S Oghalai

John Oghalai (born December 14, 1968) is an American physician and scientist. He is the Leon J. Tiber and David S. Alpert Chair in Medicine at the University of Southern California Keck School of Medicine and chair of the USC Caruso Department of Otolaryngology. Oghalai is an otolaryngologist. His research focuses on anatomical and molecular mechanisms in hearing and in ear and hearing disorders.

Early life and education Oghalai grew up in Madison (Wisconsin) with his father Rahim, mother Karen (née Herbert), and brother Mark, who also became a doctor. Oghalai went to a Madison High School and became an Eagle Scout in 1983. He received a Bachelor of Science degree in electrical engineering in 1990, and his medical degree in 1994, both at the University of Wisconsin at Madison.

Career

In 2003, Oghalai joined the faculty at the Baylor College of Medicine as an assistant professor. He served as director at The Hearing Center at Texas Children's Hospital in Houston, TX in 2005. He became an associate professor at Baylor in 2009. to become chair of the Caruso Department of Otolaryngology at the Keck School of Medicine.

As an otolaryngology clinician, Oghalai has treated patients with issues that include noise-induced hearing loss, In addition, Oghalai treated rare diseases such as cholesteatoma.

Research

In a 2000 study, Oghalai and colleagues examined incidence of benign paroxysmal positional vertigo (BPPV) in geriatric patients at a Houston hospital. They found that 9% of the sample population had undiagnosed BPPV,

To help understand mechanisms of hearing loss brought on by explosive pressures such as those soldiers experience when exposed to roadside bombs, in 2013 Oghalai and his team studied blast effects on hearing in mice. They found that the main traumatic damage leading to noise-induced hearing loss was to cochlear hair and nerve cells, the cells responsible for translating pressure waves into the nerve signals in hearing.

In 2018, Oghalai and colleagues studied molecular dimensions of noise-induced hearing loss in mice by using optical coherence tomography, an imaging technique that allows in vivo (instead of invasive) observation and measurement. They found that after blasts damage hair cells, there is also a build up of ionized potassium in cochlear fluid.

In 2022 Oghalai and colleagues published results for a longitudinal study on the effects of cochlear implants on deaf children with developmental delays. They compared cohorts of children who received the implants to a cohort of children who, due to insurance protocols, were only given hearing aids. The children who received implants showed improved cognitive and behavioral functioning.

Personal life John Oghalai is married to Tracy Nguyen-Oghalai, a rheumatologist. They have two sons, Kevin and Tom.

Selected publications