Gabriel Pantelias

Gabriel E. Pantelias was a Greek radiobiologist and cytogeneticist known for his pioneering work in biological dosimetry, including the development of the premature chromosome condensation (PCC) assay and a standardized G2-assay for predicting individual radiosensitivity. He was an emeritus Director of Research at the Institute of Nuclear and Radiological Sciences, Technology, Energy & Safety (INRASTES) within the National Centre for Scientific Research "Demokritos" (NCSR Demokritos) in Athens, Greece. Pantelias authored over 110 peer-reviewed publications and received the Bacq and Alexander Award in 2020 from the European Radiation Research Society.

Early life and education Pantelias was born in Naxos, Greece. He was an expert for the International Atomic Energy Agency (IAEA) on missions related to radiobiology, biodosimetry, and radiation protection.

He also created a standardized G2-assay (a test to predict how sensitive someone is to radiation) for predicting individual radiosensitivity.

His work explored chromosome breakage, repair, and rearrangement; conversion of DNA damage into chromatid breaks; formation of chromosomal aberrations at various cell cycle stages; effects of different radiation qualities (including high-LET); non-targeted effects; genomic instability; and biomarkers for biodosimetry.

Pantelias published over 110 peer-reviewed articles and contributed to more than 170 international conference proceedings, with over 3,300 citations.

Awards and recognition Pantelias received the George V. Metzger Award in 1984 from the Department of Biochemistry & Biophysics at the University of Rochester. He also received the Bacq and Alexander Award from the European Radiation Research Society in 2020 for his contributions to radiobiological sciences and radiation cytogenetics. Kulka U, et al. (2017). "RENEB – Running the European Network of biological dosimetry and physical retrospective dosimetry". International Journal of Radiation Biology. 93(1):2–14. Terzoudi GI, et al. (2015). "Stress induced by premature chromatin condensation triggers chromosome shattering and chromothripsis at DNA sites still replicating in micronuclei or multinucleate cells when primary nuclei enter mitosis". Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 793:185–198. Pantelias GE, Terzoudi GI (2011). "A standardized G2-assay for the prediction of individual radiosensitivity". Radiotherapy and Oncology. 101(1):28–34. Pantelias GE, Maillie HD (1984). "The use of peripheral blood mononuclear cell prematurely condensed chromosomes for biological dosimetry". Radiation Research. 99(1):140–150.