Elizabeth P. Carpenter

Elisabeth P. Carpenter is a British structural biologist who is a professor at the Nuffield Department of Medicine in Oxford. She solved the three-dimensional structure of human membrane proteins using X-ray crystallography. Carpenter uses X-ray crystallography to understand the atomic positions within proteins.

Early life and education Carpenter studied biochemistry at the University of Cambridge from 1981 to 1985. She moved to Birkbeck, University of London for doctoral research from 1985 to 1989, where she studied biochemistry and crystallography. After completing her doctorate, Carpenter moved to the National Institute for Health Research, which was based at Imperial College London and solved the structures of proteins involved in DNA repair. Subsequently, from 2009 to 2020, she worked at the Structural Genomics Consortium at the University of Oxford with a focus on human membrane proteins.

Research Carpenter is interested in understanding the structure and function of proteins. She studies proteins embedded within cell membranes.

Carpenter was the first to describe the structure of the human ABC-transporter ABC10, a mitrochonridal protein that is important in the production of heme. She has studied premature ageing syndromes that are caused by failure of the lamin proteins, and the role of the metalloprotease ZMPSTE24. She has also studied human two-pore potassium channels (K2Ps), protein that gives rise to the background leak current that contributes to membrane potential.

Selected publications