David Isserman

David Isserman (born March 31, 1983) is an American entrepreneur and conservationist living in Lisbon, Portugal. He is the founder of Isserman Ventures, a firm that invests in and provides operational management to direct-to-consumer e-commerce companies. From 2020 to 2026, he served on the board of directors of The Explorers Club.

Isserman co-founded RareShare, an online platform for rare disease communities, in 2008, and founded Venin Royale, a skincare company in Boulder, Colorado, in 2013. He has supported rewilding projects in Portugal's Alentejo region, including the reintroduction of endangered Sorraia horses through an Explorers Club flag expedition. At age 14, he approached A.G. Edwards to offer technology consulting services; Alfred Goldman, a corporate vice president at the firm's brokerage subsidiary, later nominated him for the St. Louis Business Journals 30 Under 30 list, to which he was named in 2006.

RareShare In 2008, while attending Columbia Business School, Isserman co-founded RareShare with Eric Steele. RareShare won the social venture category at the 2008 Pace Pitch Contest hosted by Pace University's Lubin School of Business. In December 2008, TechCrunch described the platform as covering more than 200 rare diseases and partnering with the National Institutes of Health and the Canadian Organization for Rare Disorders. RareShare grew to more than 850 communities before Isserman exited in 2014.

Venin Royale In 2013, Isserman founded Venin Royale, a skincare company in Boulder, Colorado, that used king cobra venom peptides in its products. The products were developed with neuroscientist Paul Reid. In 2025, Isserman contributed to the development of the club's membership app. The Explorers Club Flag No. 179 expedition team in Portugal's Alentejo region, 2024. From left: Ruth Ganesh, Kate Moore, Anna Isserman, David Isserman (holding flag), Princess Diana d'Orléans, Duchess of Cadaval, Gonçalo Matos, and José Fontes of Rewilding Portugal. He returned the flag at the 2025 ECAD ceremony.

In 2025, Isserman led the PaleoDiscovery Team on the Dino Dawn Expedition, an Explorers Club flag-bearing paleontological dig in Portugal's Algarve region led by paleontologist Ricardo Araújo.

Honors In 2023, Duarte Pio, Duke of Braganza, made Isserman a Knight of the Order of Saint Michael of the Wing, a dynastic order of the non-reigning House of Braganza. They moved from the United States to Lisbon, Portugal, in 2022.