Cyrus II of Edessa

Cyrus II (Syriac: Qiyore or Qūrā; died 498) was the archbishop of Edessa and metropolitan of Osrhoene from 471 until his death.

Cyrus succeeded Nonnus as bishop in 471.

In the year 809 of the Seleucid era (either 496 or 497), during an outbreak of the "disease of tumours", Cyrus urged the people to make silver litter for carrying the Eucharistic vessels during the commemorations of martyrs. Eutychianus, husband of Aurelia, gave 100 denarii for its construction. The "disease of tumours", which is said to have made some blind, has not been securely identified. It may have been an early outbreak of bubonic plague before the first pandemic began in the 540s.