Cheryl L. Willman

Cheryl Lynn Willman (born November 5, 1954) is an American cancer researcher and executive director of Mayo Clinic Cancer Programs at the Mayo Clinic Comprehensive Cancer Center.

Early life and education Willman was born on November 5, 1954, in Hartford City, Indiana, but she grew up in Iowa. She was born into a practicing Lutheran family as her grandfather played the church organ while her father worked as a nonordained ministry associate and administrator for the Evangelical Lutheran Church in America. Growing up, Willman attended Bettendorf High School where she served as class vice president and newspaper journalist. Upon graduating from high school, Willman enrolled at St. Olaf College where she majored in chemistry and graduated in 1977. She originally intended to enroll in law school but had become disillusioned with the American legal system due to the Vietnam War. During her third year at the Mayo Clinic, she stepped away from the school for six months to join the National Institutes of Health’s medical science training program. During her time with the program, she was mentored by immunologists Anthony Fauci and Alfred D. Steinberg. During her early tenure at the UNM School of Medicine, Willman focused her research on developing cancer diagnostics and therapies by using genomic, next generation sequencing and computational technologies to identify cancer-causing DNA mutations. As such, she was awarded one of the first NIH Physician-Scientist Awards for her research. In 1993, Willman found that the loss of only half of the normal pair of IRF-1 genes could lead to someone developing leukemia. She came to this conclusion by studying the IRF-1 gene of 13 patients who had adult leukemia or myelodysplasia. In 1999, Willman was appointed director of the UNM Comprehensive Cancer Center which she helped expand from a team of 12 physicians to 143.

As she continued her tenure at UNM School of Medicine, Willman was named the Maurice & Marguerite Liberman Distinguished Chair in Cancer Research and became a Full Professor of Pathology and Medicine. In these roles, she began to research and study Acute lymphoblastic leukemia in Hispanic and Native American children who were not responding to standard therapies. Her research team discovered that these children had Philadelphia-like ALL caused by a genetic mutation specific to them. In 2013, she was honored with the "La Estrella" award from the YWCA for her "distinguished medical career and her leadership role in the field of cancer research." Two years later, she chosen to receive a 2015 STC.UNM Innovation Fellow Award in recognition of her achievements as "one of the University of New Mexico’s leading innovators."

In 2017, Willman was elected a Fellow of the National Academy of Inventors for having a "tremendous impact on fostering a culture of innovation at the UNM Comprehensive Cancer Center and The University of New Mexico that is felt on local, national, and international levels." During the COVID-19 pandemic, Willman encouraged social distancing and wearing a face mask. In 2021, she was named executive director of Mayo Clinic Cancer Programs and director of the Mayo Clinic Comprehensive Cancer Center.

Personal life Willman married pathologist Ross Zumwalt in 1988 and they have one son together.