Bernhard Zondek

Bernhard Zondek (; 29 July 1891 – 8 November 1966) was a German-born Israeli gynecologist who developed the first reliable pregnancy test in 1928.

Biography Bernhard Zondek was born in Wronke, Germany, now Wronki, Poland. He studied medicine in Berlin, graduating in 1919. He worked under Karl Franz at the university women's clinic in Berlin Charité, where he specialized in obstetrics and gynecology. His older brother, Hermann Zondek, was a professor at the Humboldt University of Berlin and a pioneer of modern endocrinology.

Medical career Germany In 1926, he became ausserordentlicher Professor, and in 1929, chief physician of the obstetrics and gynecology ward at the municipal hospital of Berlin-Spandau. When the Nazis came to power in 1933, he was dismissed from his posts.

Sweden He left Germany for Stockholm, where he applied for permission to work as a physician in Sweden. Meanwhile, he started working as an unpaid scientist at the Biochemical Institute of Stockholm University. In September 1934 he turned directly to the Swedish king to get a practitioner's license. The Swedish Medical Association were asked for their opinion, and while a narrow majority voted to grant him permission for scientific work only (excluding him from clinical practice), the rest wanted to deny him permission altogether. When the media reported on the case, the chairman of the medical association wrote pieces discrediting Zondek and casting suspicion upon him in the media, and a protest against Zondek gathered over 1,000 practitioners' signatures, amounting to a third of the Swedish physicians. These expressions of hostility and Jew-hatred from his colleagues made Zondek decide that he could not stay in Sweden.

Israel In the fall of 1934, he immigrated to Mandatory Palestine, where he was appointed professor of obstetrics and gynecology at the Hebrew University of Jerusalem, and head of obstetrics and gynecology at Hadassah Hospital.

Medical discoveries Zondek was one of the proponents of the inter-dependence of the endocrine glands under the control of the pituitary. His studies on pituitary-ovary interaction were instrumental in establishing this fundamental tenet. He discovered that the chorionic tissue of the placenta had endocrine capacity and this led to diagnostic techniques important for the recognition and treatment of hydatidiform mole and chorionic carcinoma.

Awards and recognition In 1956, Zondek received the Solomon Bublick Award of the Hebrew University of Jerusalem. In 1958, he was awarded the Israel Prize, in medicine.