Antonello Paparella

Antonello Paparella is a food microbiologist and academic. He is a professor of Food Microbiology in the Department of Bioscience and Technology for Food, Agriculture, and Environment at the University of Teramo, Italy. His research work has focused on different aspects of food microbiology, including microbial ecology of foods, pathogens, food preservation, antimicrobial resistance, and biofilm formation, with an emphasis on the application of essential oils and hydrolates in food preservation and in food environments.

Education In 1985, Paparella completed his graduation in Veterinary Medicine at the University of Bari, Italy. In 1987, he earned his Diploma of Veterinary Pathological Anatomy and Food Safety from the University of Bologna, Italy.

Career From 1987 to 1994, Paparella worked as a research director at the BeCa SpA, Bologna. Subsequently, he assumed the position of R&D manager at Fiorucci SpA, Rome, which he maintained till 1996. At the Food Assistance and ITA (ITA Life Analytics), he was employed as a scientific director in 1996. Additionally, he held the role in the Italian group of experts at the Italian Standardisation Body (UNI), as well as in the group of experts "Bilan des viands" at the European Union. and other pathogens in ready-to-eat foods. In this respect, his team has investigated the antimicrobial mechanisms of essential oils using flow cytometry, and highlighted different mechanisms of action for thyme, cinnamon, and oregano essential oils. In a collaborative study using electron paramagnetic resonance, he demonstrated that oregano essential oil targets the cell membrane of Listeria monocytogenes. He has also emphasized strategies for preventing or eliminating biofilms using natural antimicrobials, highlighting that hydrolates (Citrus aurantium) and essential oils (Corydothymus capitatus and Origanum hirtum) may regulate Listeria biofilms on specific food-contact surfaces, particularly avoiding biofilm growth on polystyrene or stainless steel surfaces.

Paparella's research has also explored the microbial ecology of traditional Italian fermented meats, exemplified by studies identifying dominant bacterial species such as Lactobacillus curvatus in Italian sausage. Later in 2020, Lactobacillus curvatus was reclassified as Latilactobacillus curvatus. He has investigated the role of biogenic amines (BAs) as quality and stability indicators in meat and has highlighted that excess BAs in seafood can cause life-threatening health issues. His team carried out research aimed at understanding spoilage organisms, specifically investigating the occurrence and role of organisms such as Shewanella spp. in muscle foods.

Paparella has also addressed antimicrobial resistance by investigating how integrating essential oils with antibiotics can increase bacterial sensitivity to antimicrobials. His team identified that these combinations against resistant Salmonella strains significantly decreased the antibiotic's minimum inhibitory concentration (MIC), thus restoring microbial sensitivity in antibiotic-resistant strains. Moreover, he also demonstrated that antimicrobial efficacy can be significantly increased by combining essential oils with antibiotics in a synergistic manner.

Selected articles