Anne Williams-Isom

Anne Williams-Isom (born November 17, 1964) is an American government official, academic, lawyer and former nonprofit executive who served as New York City deputy mayor for health and human services from January 2022 to March 2025. She also served as acting first deputy mayor of New York City from the departure of former first deputy mayor Sheena Wright in the morning on October 8, 2024 until the appointment of Maria Torres-Springer as first deputy mayor later that same day in accordance with Executive Order 45 that was issued and signed on September 26, 2024 by Mayor Eric Adams that automatically delegates the duties of first deputy mayor to the deputy mayor for health and human services if for any reason the position of first deputy mayor becomes vacant or the first deputy mayor is for any reason unable to perform the duties of first deputy mayor. She holds the James R. Dumpson chair of child welfare studies at Fordham Graduate School of Social Service. She was the chief operating officer and later the chief executive officer of the Harlem Children's Zone.

Early life Williams was born on November 17, 1964, in Queens, New York City, to Edna and Atthille Williams. Williams was a student at St. Catherine of Sienna School in St. Albans, Queens. Her mother emigrated to the United States from Trinidad and Tobago. She graduated from the Dominican Commercial High School.

Williams-Isom is the James R. Dumpson chair of child welfare studies at Fordham Graduate School of Social Service.

In December 2021, Mayor-elect Eric Adams named Williams-Isom as the incoming deputy mayor for Health and Human Services.