Ana Cristina Rego

Ana Cristina Rego is a Portuguese neurologist. She is a professor at the University of Coimbra in Portugal and is head of the research group on Mitochondria and Neurodegenerative disorders, researching on topics such as Alzheimer's disease, Huntingdon's disease, and Parkinson's disease. She is presently president of the Portuguese Society of Neuroscience.

Training Ana Cristina Carvalho Rego obtained the Bachelor degree in Biology in 1991 the Master degree in cell biology in 1994 and a PhD in Cell Biology in January 1999 from the University of Coimbra, under the supervision of Prof. Catarina Resende de Oliveira.

Career Rego began work in 1997 as a teaching assistant at the Faculty of Medicine of the University of Coimbra (FMUC). After obtaining her doctorate, she became an assistant professor in 1999, receiving tenure in 2004 and Aggregation (Agregação) in 2010. She became an associate professor in 2019, teaching classes in biochemistry, neuroscience and neurobiology at the Centre for Neuroscience and Cell Biology (CNC) at the university. During the period 1998-2000 she was also a post-doctoral researcher in the laboratory of Prof. David G. Nicholls, at the University of Dundee in Scotland and visiting researcher at the David Nicholls Lab of the Buck Institute for Research on Aging, in Novato, California.

Publications Rego acts as a reviewer for many scientific journals. She has published over 125 peer-reviewed journal articles. Some of those for which she has been the senior author are listed below. Together with Carlos B. Duarte and Catarina Resende de Oliveira she has written a 700-page textbook for medical students, entitled Neurosciences

AC Rego, CR Oliveira. Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases. Neurochemical research 28 (10), 1563-1574 509 AC Rego, MS Santos, CR Oliveira. Oxidative stress, hypoxia, and ischemia-like conditions increase the release of endogenous amino acids by distinct mechanisms in cultured retinal cells. Journal of neurochemistry 66 (6), 2506-2516 AC Rego, MS Santos, CR Oliveira. Influence of the antioxidants vitamin E and idebenone on retinal cell injury mediated by chemical ischemia, hypoglycemia, or oxidative stress. Free Radical Biology and Medicine 26 (11-12), 1405-1417 AC Rego, MW Ward, DG Nicholls. Mitochondria control ampa/kainate receptor-induced cytoplasmic calcium deregulation in rat cerebellar granule cells. Journal of Neuroscience 21 (6), 1893-1901 AC Rego, MS Santos, CR Oliveira. Adenosine triphosphate degradation products after oxidative stress and metabolic dysfunction in cultured retinal cells. Journal of neurochemistry 69 (3), 1228-1235 AC Rego, CR Oliveira. Dual effect of lipid peroxidation on the membrane order of retinal cells in culture. Archives of biochemistry and biophysics 321 (1), 127-136 37 AC Rego, MS Santos, CR Oliveira. Glutamate-mediated inhibition of oxidative phosphorylation in cultured retinal cells. Neurochemistry international 36 (2), 159-166 AC Rego, LP de Almeida. Molecular targets and therapeutic strategies in Huntington's disease. Current Drug Targets-CNS & Neurological Disorders 4 (4), 361-381