Amy Karle

Amy Karle (born 1980) is an American artist, bioartist, and futurist whose work focuses on the relationship between technology and humanity, specifically how technology and biotechnology impact health, humanity, society, evolution, and the future. Karle combines science and technology with art and is known for using living tissue in her work. sponsored by the U.S. Department of State, for a cultural exchange initiative in conjunction with the Copernicus Science Center in Poland where she led workshops focusing on women's empowerment in STEAM fields. Karle is an alumnus of the School of Art and Design at Alfred University and Cornell University where she received degrees in Art and Design and Philosophy.

Karle was born with a rare condition, aplasia cutis congenita, missing a large region of skin on her scalp and also missing bone in her skull. She underwent a series of experimental surgical procedures as a child. The skin was repaired by tissue expansion surgery that was considered dangerous and experimental at the time that it was performed. This early experience also inspired her interest in the links between biology, medical futuring and art.

Karle has created a number of artworks and performances using biofeedback and neurofeedback including:

Karle was named as one of the BBC's 100 women in 2019. It has been exhibited internationally.

Internal Collection (2016–2017) is a series of garments based on human anatomy. The fabrication consists of 3D body scanning, computer-aided design, laser cutting, and hand-sewing techniques to create representations of internal body systems.

The Body and Technology: A Conversational Metamorphosis (2017) is a collection of 2D artworks by Amy Karle made by hand and with artificial neural networking, machine learning, and artificial intelligence. In this body of work, Karle coupled artificial intelligence in healthcare with generative design to devise a system for leveraging AI in the diagnosis of disease, with generative CAD designing replacement parts, and 3D bioprinting to create implants.

Morphologies of Resurrection (2020) is a series of 6 sculptures created as part of a Smithsonian residency, and exhibited at the Smithsonian Institution. Karle's process examined the possibilities of reconstructive technologies and future evolution through biotechnological advancements. The artworks are novel evolutionary forms based upon extinct species to explore “hypothetical evolutions through technological regeneration”, 3D printed in biocompatible material.

Artificial intelligence Her AI and bio-AI hybrid artworks have been in museum exhibitions including: Artificial Intelligence: AI / The Other I Ars Electronica Linz, Austria,