Amanda Fosang

Amanda Jane Fosang is a biomedical researcher who has pioneered arthritis research in Australia.

Career Fosang is a principal research fellow with the National Health and Medical Research Council (NHMRC) of Australia who has an established career researching arthritis and cartilage biology in health and disease.

More recently, Fosang's group has been studying the degradation products generated by these enzymes, and how these products might regulate cellular function. Some studies are done in explant and cell culture systems, or with highly purified enzymes and substrates in vitro. Other studies use unique, genetically modified mice that have been engineered to resist cartilage destruction. Studies with these mice can provide valuable insights into the mechanisms of joint remodelling in development and disease. Her studies on cartilage biology and arthritic diseases will identify new target molecules and/or activities, for the development of disease-modifying arthritis therapies.

Professional service Fosang joined the board of directors for the Osteoarthritis Research Society International (OARSI) in 2012 and was appointed Chair of the OARSI Asian Task Force in 2013. She is the first Australian appointed to the Journal of Biological Chemistry as an associate editor.

Awards Member of the Order of Australia, 2021 NHMRC Principal Research Fellow, 2006, 2010 Barry Preston Award, Matrix Biology Society of Australia & New Zealand, 2007 Discovery Award for Excellence in Research Achievement, MCRI, 2006