Alison H Holmes

Early life and education Holmes went to school in Dar es Salaam, Tanzania. Her father was a doctor in Nigeria. Holmes completed her Bachelor of Medicine, Bachelor of Surgery degree in medicine at the University of Cambridge and St George’s Hospital Medical School. She specialised in Infectious Diseases and General (Internal) Medicine.

Research and career Antimicrobial resistance (AMR) represents a major threat to healthcare. There are increasing numbers of bacteria that can no longer be treated with antibiotics. At Imperial College London Holmes leads Centre for Antimicrobial Optimisation, a research centre that looks to tackle drug-resistant infection. She is Director of the National Institute for Health Research (NIHR) Health Protection Research Unit in Healthcare Associated Infections and AMR.

In 2023, Holmes launched the Centres for Antimicrobial Optimisation Network (CAMO-Net), a Wellcome Trust funded research collaboration of universities based in 11 different countries, designed to address antimicrobial resistance and support antimicrobial optimisation for use in humans.

Selected publications

Birgand G, Castro-Sánchez E, Hansen S, et al., 2018, Comparison of governance approaches for the control of antimicrobial resistance: Analysis of three European countries, Antimicrobial Resistance and Infection Control, Vol:7, Comparison of governance approaches for the control of antimicrobial resistance: analysis of three European countries Holmes AH, Holmes M, Gottlieb T, et al., 2018, End non-essential use of antimicrobials in livestock, Bmj, Vol:360, End non-essential use of antimicrobials in livestock Ardal C, Outterson K, Hoffman SJ, et al., 2016, International cooperation to improve access to and sustain effectiveness of antimicrobials, The Lancet, Vol:387, , Pages:296–307 International cooperation to improve access to and sustain effectiveness of antimicrobials Holmes AH, Moore LSP, Sundsfjord A, et al., 2015, Understanding the mechanisms and drivers of antimicrobial resistance, Lancet, Vol:387, , Pages:176–187 Understanding the mechanisms and drivers of antimicrobial resistance Charani E, Holmes AH, 2013, Antimicrobial stewardship programmes: the need for wider engagement, BMJ Quality & Safety, Vol:22, , Pages:885–887 Antimicrobial stewardship programmes: the need for wider engagement

Honours and awards Holmes was elected a Fellow of the Academy of Medical Sciences (FMedSci) in 2017.

She was appointed Officer of the Order of the British Empire (OBE) in the 2021 Birthday Honours for services to medicine and infectious diseases, particularly during Covid-19.